Published by MyelinWatch:
CN045 · CN045 is a small molecule intended to help immature cells mature into cells that make myelin. Researchers are refining it before considering human testing.
CN045 is a small molecule intended to help immature cells mature into cells that make myelin. Researchers are refining it before considering human testing.
Not tested in people
Research so far is in laboratory cells or animal models.
Promising effects have been reported in human cells studied in the laboratory and in mice. These findings do not show safety or benefit in people with MS.
CN045 is not a treatment. Further development and safety work are needed before a study in people could be considered.
A paper in npj Drug Discovery described CN045, a molecule that can reach the brain and spinal cord. In the laboratory it helped immature human cells develop into cells that make myelin, and in mice it increased myelin repair.
Source: npj Drug Discovery — peer-reviewed research article ↗
